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FeaturesPlatform Features

Roadmap

Short Term

  • ⏱Agentic Control - AI-driven research workflow management
  • ⏱Milestone-based Planning - Enhanced project timeline tracking

Long Term

  • 🔮Federated multisite research collection
  • 🔮Evidence extraction, standardization and exchange
  • 🔮Multisite Networking - Research collaboration across institutions

Privacy: Our Central Pillar

Privacy
Complete Privacy Control

Healthcare research demands the highest standards of privacy protection. CareFrame makes privacy a central pillar of our platform, with advanced PHI/PII detection and protection built into every aspect.

  • 🔒Advanced PHI/PII detection and redaction
  • 🔒HIPAA and PHIPA compliant by design
  • 🔒Granular privacy controls for each project

Security
Secure Deployment Options

Deploy CareFrame entirely within your institutional firewall, with no external dependencies required.

  • 🛡️Run locally within your firewall
  • 🛡️Use open-source LLMs for complete data sovereignty
  • 🛡️No data ever leaves your secure environment

StrategyResearch Strategy

Planning

Planning

Visual canvas for mapping research objectives and hypotheses

Research Canvas

Research Canvas

Interactive visual workspace for research planning

Objective Management

Objective Management

Hierarchical organization of research objectives

Hypotheses

Hypotheses

Create and manage testable research hypotheses

Hypothesis Generator

Hypothesis Generator

AI-assisted creation of research hypotheses

Hypothesis Testing

Hypothesis Testing

Connect hypotheses to evidence and statistical tests

Study Design

Study Design

Design and plan research studies

Protocol Development

Protocol Development

Create detailed study protocols from evidence

Session Management

Session Management

Organize and manage research projects

Team Management

Team Management

Manage research team members and permissions

EvidenceEvidence Management

LiteratureLiterature Evidence

Literature Search

Literature Search

Find and collect relevant research papers

Paper Ranking

Paper Ranking

Sort literature by relevance to hypotheses

Evidence Extraction

Evidence Extraction

Extract claims and evidence from papers

DataData-Based Evidence

Data Sources

Data Sources

Connect to various data collection sources

Model Testing

Model Testing

Statistical testing of research hypotheses

Result Interpretation

Result Interpretation

Visualize and interpret statistical results

ValidationEvidence Validation

Evidence Blockchain

Evidence Blockchain

Secure, immutable storage of research evidence

Validator Management

Validator Management

Team-based validation of research evidence

Proof Authority

Proof Authority

Cryptographic verification of evidence provenance

DataData Management

Data Cleaning

Data Cleaning

Tools for preparing and cleaning research data

Data Reshaping

Data Reshaping

Transform data structures for analysis

Data Filtering

Data Filtering

Select relevant subsets of research data

Data Merging

Data Merging

Combine data from multiple sources

Database Management

Database Management

Configure and manage research databases

AnalysisStatistical Analysis

Assumption Checking

Assumption Checking

Validate statistical assumptions for tests

Advanced Analysis

Advanced Analysis

Specialized statistical techniques

Subgroup Analysis

Subgroup Analysis

Examine effects within population subgroups

Mediation Analysis

Mediation Analysis

Test for mediating relationships between variables

Sensitivity Analysis

Sensitivity Analysis

Test robustness of findings to assumptions

Biomedical Annotation

Biomedical Annotation

Annotate medical terms in research documents

ManagementStudy Management

Participant Management

Participant Management

Track study participants and data collection

Documentation

Documentation

Maintain comprehensive study documentation

Network Sharing

Network Sharing

Share evidence and protocols across institutions

Open Source Research Platform

CareFrame

Bridging the gap between clinical data and the clinician's workbench

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Evidence Standardization Platform

Eliminate 80% of manual data standardization work while increasing evidence quality. Our AI framework ensures consistent evidence formatting across institutions, dramatically reducing interpretation errors and enabling faster insights that translate to improved patient outcomes.

Dual-Layer Evidence Exchange

Dual-Layer SystemSelect flow below
HospitalLabMedical CenterClinicCentral Messaging Real-Time Exchange
Data Flow
Real-time Exchange
Blockchain Ledger

Dual-layer system: Real-time exchange & distributed blockchain with team and role-based validation.

Clinical Workflow Solutions

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Reduced Documentation Burden

Intelligent automation that captures and structures clinical information, allowing providers to focus on patient care instead of paperwork.

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Evidence-Based Decisions

Access the latest clinical research findings in your workflow, with contextual insights linked directly to patient scenarios.

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Interdisciplinary Communication

Secure sharing of patient-critical information across specialty boundaries, ensuring coordinated care without information silos.

Stay Updated on CareFrame

Join our community to receive updates, announcements, and early access to new features

AI-Powered Research Automation

Advanced automation that streamlines research workflows while maintaining rigorous methodological standards

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Intelligent Literature Processing

AI analyzes thousands of research papers in minutes, identifying relevant studies and extracting key evidence directly related to your research questions.

  • Semantic search across multiple databases
  • Automated evidence extraction and classification
  • Real-time research landscape visualization
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Automated Statistical Validation

Ensure methodological rigor with AI that automatically verifies statistical assumptions, identifies potential biases, and validates analytical approaches.

  • Pre-analysis assumption verification
  • Automated test selection based on data characteristics
  • Interpretive guidance for complex statistical results
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Team Collaboration & Workflow

Enable seamless coordination among team members with role-based dashboards, shared workspaces, and automated progress tracking.

  • Role-based permission system
  • Real-time progress monitoring
  • Automated notification and task assignment
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Evidence Blockchain

Store validated findings in an immutable blockchain, ensuring transparency and verifiability while facilitating controlled sharing.

  • Immutable proof-of-authority validation
  • Complete methodological transparency
  • Secure multi-institutional evidence sharing

About & Press Coverage

Recent media coverage and announcements about our platform

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GritDaily

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Healthcare Startup CareFrame Introduces Novel Evidence-Based Platform for Clinical Research

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USA Today

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Open Source Healthcare Platforms Gain Momentum: CareFrame Leads the Way

Press coverage is provided for informational purposes only and does not constitute endorsement of CareFrame by the mentioned publications.

shield-lock-fillPrivacy as a Core Principle

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Complete Data Sovereignty

CareFrame runs entirely within your institutional firewall, with no data ever leaving your secure environment.

  • On-premises deployment with no external dependencies
  • Full compatibility with air-gapped research environments
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Advanced PHI Protection

Comprehensive PHI/PII detection and protection built into every aspect of the platform.

  • HIPAA and PHIPA compliant by design
  • Open-source LLMs with full privacy controls

Transform Your Research Collaboration

Open Source for Complete Transparency

Accelerate discovery, ensure methodological rigor, and streamline implementation with CareFrame's team-based research platform.

CareFrame is 100% open source, enabling full code inspection, community contributions, and customization for your organization's specific needs.

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