GitHubGitHub

FeaturesPlatform Features

Roadmap

Short Term

  • Agentic Control - AI-driven research workflow management
  • Milestone-based Planning - Enhanced project timeline tracking

Long Term

  • 🔮Federated multisite research collection
  • 🔮Evidence extraction, standardization and exchange
  • 🔮Multisite Networking - Research collaboration across institutions

Privacy: Our Central Pillar

Privacy
Complete Privacy Control

Healthcare research demands the highest standards of privacy protection. CareFrame makes privacy a central pillar of our platform, with advanced PHI/PII detection and protection built into every aspect.

  • 🔒Advanced PHI/PII detection and redaction
  • 🔒HIPAA and PHIPA compliant by design
  • 🔒Granular privacy controls for each project

Security
Secure Deployment Options

Deploy CareFrame entirely within your institutional firewall, with no external dependencies required.

  • 🛡️Run locally within your firewall
  • 🛡️Use open-source LLMs for complete data sovereignty
  • 🛡️No data ever leaves your secure environment

StrategyResearch Strategy

Planning

Planning

Visual canvas for mapping research objectives and hypotheses

Research Canvas

Research Canvas

Interactive visual workspace for research planning

Objective Management

Objective Management

Hierarchical organization of research objectives

Hypotheses

Hypotheses

Create and manage testable research hypotheses

Hypothesis Generator

Hypothesis Generator

AI-assisted creation of research hypotheses

Hypothesis Testing

Hypothesis Testing

Connect hypotheses to evidence and statistical tests

Study Design

Study Design

Design and plan research studies

Protocol Development

Protocol Development

Create detailed study protocols from evidence

Session Management

Session Management

Organize and manage research projects

Team Management

Team Management

Manage research team members and permissions

EvidenceEvidence Management

LiteratureLiterature Evidence

Literature Search

Literature Search

Find and collect relevant research papers

Paper Ranking

Paper Ranking

Sort literature by relevance to hypotheses

Evidence Extraction

Evidence Extraction

Extract claims and evidence from papers

DataData-Based Evidence

Data Sources

Data Sources

Connect to various data collection sources

Model Testing

Model Testing

Statistical testing of research hypotheses

Result Interpretation

Result Interpretation

Visualize and interpret statistical results

ValidationEvidence Validation

Evidence Blockchain

Evidence Blockchain

Secure, immutable storage of research evidence

Validator Management

Validator Management

Team-based validation of research evidence

Proof Authority

Proof Authority

Cryptographic verification of evidence provenance

DataData Management

Data Cleaning

Data Cleaning

Tools for preparing and cleaning research data

Data Reshaping

Data Reshaping

Transform data structures for analysis

Data Filtering

Data Filtering

Select relevant subsets of research data

Data Merging

Data Merging

Combine data from multiple sources

Database Management

Database Management

Configure and manage research databases

AnalysisStatistical Analysis

Assumption Checking

Assumption Checking

Validate statistical assumptions for tests

Advanced Analysis

Advanced Analysis

Specialized statistical techniques

Subgroup Analysis

Subgroup Analysis

Examine effects within population subgroups

Mediation Analysis

Mediation Analysis

Test for mediating relationships between variables

Sensitivity Analysis

Sensitivity Analysis

Test robustness of findings to assumptions

Biomedical Annotation

Biomedical Annotation

Annotate medical terms in research documents

ManagementStudy Management

Participant Management

Participant Management

Track study participants and data collection

Documentation

Documentation

Maintain comprehensive study documentation

Network Sharing

Network Sharing

Share evidence and protocols across institutions

About CareFrame

Our Mission

CareFrame bridges the gap between clinical research and patient care by creating an integrated learning health system where evidence generation, validation, and implementation happen in a continuous cycle.

The Problem We're Solving

Clinical research workflows have traditionally been fragmented, with disconnections between hypothesis generation, literature review, data analysis, and evidence sharing. This fragmentation leads to long delays in implementing evidence into practice—an average of 17 years from discovery to implementation.

Our Approach

CareFrame provides a unified platform where each phase of research builds on the last, creating a transparent, rigorous, and connected research process. By integrating all stages of research with blockchain-based evidence validation and secure knowledge sharing, we accelerate the translation of research into practice.

Open Source Philosophy

We believe that research methods should be transparent, evidence should be verifiable, and collaboration should transcend institutional boundaries. By open-sourcing CareFrame, we aim to build a community of researchers, clinicians, and developers committed to improving clinical evidence generation and application.

Future Development

Based on community feedback, we'll be expanding CareFrame's capabilities with intelligent assistants that automate routine research tasks, freeing researchers to focus on scientific questions rather than technical implementation.

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Contact

Have questions or suggestions? We'd love to hear from you.

contact@careframe.ai

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